drug resistance of isolated strains of pseudomonas aeruginosa from burn wound infections to selected antibiotics and disinfectants

Authors

parviz owlia

horieh saderi

sadegh mansouri

sirus salemi

hossein ameli

abstract

background and objectives: infection is the most common problem following burn injury. selection and dissemination of intrinsic and acquired resistance mechanisms increase the probability of burn wound colonization by resistant species including pseudomonas aeruginosa. multi-drug resistant pseudomonas aeruginosa has frequently been reported as the cause of nosocomial outbreaks of infection in burn wards or as colonizers of the wound of burned patients. therefore, this research study was conducted to compare the activity of various antibiotics and disinfectants against clinically important strains of p. aeruginosa. materials and methods: one hundred strains of p. aeruginosa were obtained as clinical isolates from burn wound infections. the antimicrobial activity of antibiotics was tested by disk diffusion method of kirby-baur. for disinfectants, 30 μl of each of them was placed on sterile blank disk and studied by disk diffusion method. results: the frequency of resistant strains to kanamycin, tobramycin, amikacin, cefotaxime, carbenicillin, ceftazidime, ceftizoxime, cefixim, ciprofloxacin, cefazolin, cephalexine, and ceftriaxone was 100, 93, 95, 81, 84, 95, 94, 100, 99, 100, 100, and 92 respectively. the averaged diameter of inhibition zone for chlorhexidine (0.2%), povidione iodine (10%), cetrimide-c (3.5%), dekosept, hypochlorite (10%), micro 10+ (2%), deconex 53+ (2%), and ethanol (70%) was 14.4 ± 1.9 mm, 10.6 ± 1.3 mm, 9.1 ± 2.6 mm, 8.6 ± 2.2 mm, 26.9 ± 5.2 mm, 6.58 ± 1.5 mm, 8.3 ± 2.2 mm, and 6 ± 0.0 mm respectively.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Drug resistance of isolated strains of Pseudomonas Aeruginosa from burn wound infections to selected antibiotics and disinfectants

Background and Objectives: Infection is the most common problem following burn injury. Selection and dissemination of intrinsic and acquired resistance mechanisms increase the probability of burn wound colonization by resistant species including Pseudomonas aeruginosa. Multi-drug resistant Pseudomonas ae...

full text

Antibiotics and Heavy Metal Resistance of Three Strains of Pseudomonas Aeruginosa Isolated from Different Ecological Areas

Abstract Bachground and Objective: most of environmental microorganisms have the genes resistance to antibiotics and metals. The aim of the current study was to survey resistance pattern to some antibiotics and heavy metals in three pseudomonas aeruginosa isolated from different ecological areas. Material and Methods: first, the isolates were identified by biochemical methods and phylogenetic a...

full text

Synergistic Effect of Probiotic Bacteria and Antibiotics on Antibiotic-resistant Strains of Pseudomonas Aeruginosa Isolated from Patients with Burn Wounds

Background: Burn infections are one of the leading causes of death in the world. Antibiotic resistance is a major concern among the medical community. In this study, we investigated the effect of common probiotic strains on multidrug-resistant Pseudomonas aeruginosa strains. Methods: Strains of Pseudomonas aeruginosa from burn wounds of patients were isolated. Then pathogens were biochemically ...

full text

PLASMID MEDIATED METAL AND ANTIBIOTIC RESISTANCE IN PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM BURN PATIENTS

Pseudomonas aeruginosa is a leading cause of bum infections, and antibiotic- resistant strains of this bacterium are emerging due to extensive application of antibiotics in the bum unit of hospitals. In this study 50 strains of P. aeruginosa were isolated from bum patients infected with this micro-organism in the bum unit of a general hospital in Kerman, Iran over one year [May 1999-ApriI20...

full text

Pseudomonas aeruginosa serotypes and resistance to antibiotics from wound swabs.

INTRODUCTION/AIM Pseudomonas aeruginosa (P. aeruginosa) is the most common cause of wound infections, following the disruption of the skin or mucous membranes integrity. The aim of this study was to analyze of the presence P. aeruginosa in wound swabs, antibiotics susceptibility testing, determination of the minimum inhibitory concentrations (MICs) of antibiotics, testing of the metallo-β-lacta...

full text

efflux mexab-mediated resistance in multidrug and pan-drug resistant strains of pseudomonas aeruginosa isolated from patients with burn and wound infections

conclusions this study represented an increasing rate of mdr p. aeruginosa in burn and wound samples. efflux mexab genes were detected in all mdr and pdr strains. the p. aeruginosa strain isolated from burn cases showed higher drug resistance and pdr resistance was only noted in a burn sample. materials and methods one-hundred and fifty p. aeruginosa were isolated from burn and wound infections...

full text

My Resources

Save resource for easier access later


Journal title:
iranian journal of pathology

Publisher: iranian society of pathology

ISSN 1735-5303

volume 1

issue 2 2006

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023